The Future of Parkinson’s Care: Inside Washington University’s APDA Center for Advanced Research

Parkinson’s research happening at Washington University’s APDA Center for Advanced Research The American Parkinson Disease Association (APDA) is proud to support nine Centers for Advanced Research which, along with a variety of funded grants and fellowships, are the backbone of our research program. At the Centers, some of the most compelling Parkinson’s disease (PD) research is underway […]

Carbidopa/Levodopa and its relationship to Vitamin B6 and Vitamin B12

People with Parkinson’s disease (PD) often hear about how protein can interfere with carbidopa/levodopa, but fewer realize that it is also important to pay attention to Vitamin B6 and B12. Carbidopa/levodopa can interfere with Vitamin B6 and Vitamin B12 processing, causing deficiencies in these vitamins. Low levels of Vitamin B6 and B12 can cause or […]

Gastroparesis and Parkinson’s disease

Gastrointestinal (GI) difficulties can be among the most bothersome of the non-motor symptoms caused by Parkinson’s disease (PD). Constipation, which involves the slowing down of the large intestine or lower gut is the most common of the GI symptoms, affecting 80-90% of people with PD. However, slowing down of the stomach or upper gut, also known […]

Parkinson’s Perspectives: Living with Young Onset Parkinson’s

We spoke with three people who are living with young onset Parkinson’s disease (YOPD), also called early onset PD, which describes diagnoses received before age 50. Each interviewee brings a distinct perspective on navigating PD at an earlier stage of life, sharing the unique challenges they’ve faced, the unexpected ways PD has reshaped their identities, the […]

Paraquat & Parkinson’s Disease: A Public Health Crisis — and Why We Must Act Now

Paraquat is banned in 70+ countries, but still legal in the US For the Parkinson’s community, this isn’t abstract science, it’s personal reality. Studies have shown that people exposed to paraquat are more likely to develop Parkinson’s disease (PD) than those who are not exposed. And thousands of families across the U.S. have now pursued […]

Tracking the Impact: 2025 APDA-Funded Parkinson’s Research

Since 1961, the American Parkinson Disease Association (APDA) has supported innovative scientists working to understand Parkinson’s disease (PD), improve treatments, and move closer to a cure. In 2025, APDA-funded investigators continued to drive high-impact discoveries throughout the Parkinson’s disease landscape, advancing knowledge in protein biology, brain imaging, environmental risks, and gut health, among others. These […]

Seasonal Depression, Depression, and Parkinson’s Disease

Understanding the Connections Between Parkinson’s and Depression The motor symptoms of PD include tremors, stiffness, and slowed movement, but PD can also cause many non-motor symptoms that can profoundly affect quality of life. Depression is one of the most common non-motor symptoms of Parkinson’s disease (PD) and is treatable, yet often overlooked. Sometimes, people with […]

Two New Parkinson’s Therapies Enter Final Stages of Clinical Trials

New treatments on the Horizon for Parkinson’s Two new therapies are entering the final stages of clinical trials before potential FDA approval. One is a novel dopamine-based therapy for motor symptom management, and the other is a stem cell therapy poised to replace the lost brain cells of Parkinson’s disease (PD). Together, they represent two […]

Parkinson’s Disease and the Gut: Additional Questions Answered

On a recent episode of APDA’s Dr. Gilbert Hosts, Dr. Gilbert spoke with Dr. Malu Gamez Tansey, the James A. Caplin, MD Chair in Alzheimer’s Disease at Indiana University School of Medicine and Director of Neuroimmunology Research Group, with expertise in the relationship between gut inflammation and Parkinson’s disease (PD). We covered a lot of ground […]